Eleman Pars Abnoos

Aphtous Treatment by Golnar-e-farsi

Aphtous Treatment by Golnar-e-farsi

Punica granatum  L. var pleniflora, locally  known  as “Golnar-e-farsi,” is  an important medicinal plant  in  some  northern  areas  of  Iran.  Its flowers  are  used  as  the astringent,  hemostatic,  antibacterial, antifungal, and antiviral  properties  and  also  for  treatment of  wounds, bronchitis, diarrhea, digestive problems, male sex power  reconstituent,  and  dermal  infected  wounds  in Unani medicinal  (Iranian traditional medicine) literature. The topical use of  pomegranate  preparations is  shown to be  effectively  useful for controlling  oral  inflammation,  as well as  bacterial  and  fungal  counts  in  periodontal disease and Candida-associated  denture  stomatitis.  A hydroalcoholic extract of P.  granatum fruit, known  as  HAEP, is  reported to  be  effective  against Staphylococcus, Streptococcus, Klebsiella, and Proteus species, as well as Escherichia coli. An experiment was conducted for the evaluation of the effect of the alcoholic and water extracts of P. granatum var. pleniflora on Recurrent Aphthous stomatitis. It is one of the most common problems seen in children and adults. Studies showed that the occurrence of Aphtous stomatitis. ranges from 2% to 50% between different population groups. This problem  is  characterized  by recurring,  painful, small  oral  mucosal  ulcers  with  a round or oval aspect that mostly appear in keratinized  mucosa, cheeks, and on the surface of the mouth under the tongue. There are several etiologic reasons responsible for this problem. The  etiology  of  Aphthous stomatitis  is  not  perfectly clear, but a positive family tree is seen in about one-third of the patients and there is a  genetic  background in  some  groups. In  some  of  the  patients an  unusual  hematologic  background  is  seen  as  a  decrease  in Fe, ferritin,  folate,  and  B12. The  other  etiologic  reasons  are stress, trauma, and cessation of smoking, whose mechanism is  not yet accurately clarified.  Some  patients  claim  that  Aphthous stomatitis occurs  in  relation  to  the  menstrual  cycle  and allergy  to  certain foods.  The  results  show  that  the  alcoholic  and  water  extracts  of  P.  granatum var. pleniflora have a meaningful therapeutic  effect  on  minor Aphthous stomatitis. Results from the antioxidant activity and its relation to total phenolics show  that P.  granatum var. pleniflora  and  P.granatum  var. Sweet Alak  are  rich  in  phenols. The water and alcoholic extracts of P.  granatum  var pleniflora decreased  the entire time of  complete  treatment,  and  the  treatment  was  meaningfully satisfactory for patients who participated  in  this experiment.

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